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Table 1 Effect of Bax genotype on properties of muscle colonies formed by the progeny of individual myogenic cells in vitro.

From: Immortalization of mouse myogenic cells can occur without loss of p16INK4a, p19ARF, or p53 and is accelerated by inactivation of Bax

Property

Bax-positive ave ± SE (n)

Bax-null ave ± SE (n)

Significance*

Number of nuclei per colony

428 ± 17 (341)

486 ± 22 (303)

P < 0.05

Number of mononucleate cells per colony

131 ± 7.0 (341)

191 ± 8.6 (306)

P < 0.0001

Percentage of nuclei in multinucleate cells

65.1 ± 0.9 (341)

55.5 ± 1.1 (306)

P < 0.0001

Number of nuclei per multinucleate cell

3.9 ± 0.1 (341)

3.9 ± 0.1 (305)

P > 0.5

  1. *Unpaired, two-tailed, t-test.