Figure 8

Effect of the pseudosubstrate peptide inhibitor of PKCζ (PSζ) on PLD activity. Cells were pretreated with 50 μM myristoylated PSζ for 1 hour before the addition of 2 μM PHE for 15 min. PLD activity was then measured as described in Methods. Data are expressed as the fold increase in PLD activity above basal (untreated cells). * Value significantly different from PHE alone, p < .05.