Different classes of mean square displacement of tracked nuclear vimentin particles. a) Mean squared displacement (MSD) of four representative modes of particle mobility (x-axis: acquisition time in seconds; y-axis: MSD). Roman numbers: I) confined diffusion; II) obstructed diffusion; III) normal diffusion; IV) directed motion (The numeration refers to indicated trajectories in Figure 3a). b) The four different mobility classes are represented by particle trajectories. The trajectories correlate to the numbers indicated by arrows in Figure 3a.