Skip to main content
Figure 2 | BMC Cell Biology

Figure 2

From: Trapping of normal EB1 ligands in aggresomes formed by an EB1 deletion mutant

Figure 2

Perinuclear EB1-ΔN2-GFP aggregate formation is microtubule-dependent. Panel A. Still image from living cells containing EB1-ΔN2-GFP aggregates. Panel B. The cells shown in panel A following 90 min incubation with 5 μg/ml nocodazole. Arrows indicate the presence of small peripheral aggregates. Panel C. Still image from a living cell expressing EB1-ΔN2-GFP following 4 h incubation in 5 μg/ml nocodazole. Panels D-F. Images of the cell shown in panel C at 30 min intervals following nocodazole wash out. The formation of a single perinuclear aggregate is seen. Bar = 10 μm.

Back to article page