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Figure 4 | BMC Cell Biology

Figure 4

From: Inhibition of dynamin-dependent endocytosis increases shedding of the amyloid precursor protein ectodomain and reduces generation of amyloid β protein

Figure 4

Dyn I K44A inhibits Aβ formation. HEK-695 cells were transiently transfected with empty vector or dyn I K44A. Medium was collected for 24 hours and analyzed for Aβ1–40 levels by sandwich ELISA. Levels of Aβ1–40 were significantly lower in the medium of cells transfected with dyn I K44A. *, p < 0.05 by paired t-test.

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