Figure 5

Angles between chromosome territories. (a) Scheme of fixed chromosomal angles between two pairs of chromosomes as predicted by the model of genome separation with antiparallel orientation [36]. In this example, specific angles are assumed to be about 60° and 120°. A cumulative distribution plot of homologous angles in this model has a steep increase from 0 to 100% near 180° (not shown). (b) Cumulative distribution of heterologous angles in this model example. For other chromosome pairs, angles and respective sharp increases of cumulative graphs would be at other values. Cumulative plots are shown for the indicated cell types. (c-j) Experimentally observed cumulative distributions of angles between homologous (c,e,g,i) or heterologous (d,f,h,j) chromosome territories in the indicated cell types.