Figure 1
From: TBLR1 regulates the expression of nuclear hormone receptor co-repressors
Comparison of the amino acid sequence of TBLR1 with other family members and with the homologous proteins in other species. The proteins shown in this alignment are: TBLR1-human.............................. NP078941, TBLR1-mouse............................... NP109657, TBL1X-human.............................. NP005638, TBL1Y-human............................... NP150600, TBL1-mouse.................................. XP135950, Ebi CG4063-PA [D. melanogaster] NP477329, A. gambia str. PEST....................... EA.A.12470, Arabidopsis; protein id: At5g........ NP201533, SIR4-interacting factor; SIF2p...... NP009661, Only proteins with homology to both the LisH domain (near the amino terminus) and the WD40 domains are included in the comparison. Regions of amino acid identity are shown in black; conservative substitutions are shown in gray. The large regions of non-homology are the result of insertions in the Arabidopsis and yeast sequences that have no counterparts in the other species.