Figure 6

Survival of Ang1 and Ang2 stimulated bmECs. Death in bmECs was induced by serum starvation and relative amounts of cell death compared to 0.1%FBS control (0% survival) were measured by quantification of cytoplasmic histone-associated-DNA-fragments (mono- and oligonuclosomes) via ELISA (Roche). Ang2 (800 ng/mL) provided marginally better protection from serum-deprivation-induced cell death than did Ang1 (800 ng/mL) for bmLECs. Ang2 provided marginally worse protection from serum-deprivation-induced cell death than did Ang-1 for bmVECs and bmAECs. Results of three independent experiments were compiled for this figure. P-values of unpaired, two-tailed ttest for 95% CI are indicated.