Skip to main content
Figure 1 | BMC Cell Biology

Figure 1

From: The N-terminus and alpha-5, alpha-6 helices of the pro-apoptotic protein Bax, modulate functional interactions with the anti-apoptotic protein Bcl-xL

Figure 1

Inhibition of Bax and Bax 30–192 by Bcl-2 and Bcl-x L . A, GFP (1 μg), Bax-GFP (3 μg) or Bax 30–192-GFP (3 μg) with or without Bcl-xL (5 μg) were transfected in Jurkat cells. GFP positive cells were assessed for apoptotic nuclear damage. B, Jurkat cells were transfected with GFP (1 μg), Bax-GFP (3 μg) or Bax 30–192-GFP (3 μg) with or without Bcl-2 (5 μg) and assessed for apoptotic nuclear damage 12 hours post-transfection. The data are presented as mean ± SD derived from three-four independent experiments. *p < 0.001

Back to article page