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Table 1 Percentage of CpG methylation in the LEP, PPARG2, FABP4 and LPL promoters in undifferentiated and differentiated ASC clones at passage 4 (P4) and at senescence (Ps)

From: Dynamics of adipogenic promoter DNA methylation during clonal culture of human adipose stem cells to senescence

   Percent methylated cytosines in promoter region examined
Gene   LEP PPARG2 FABP4 LPL
Passage No.   P4 Ps P4 Ps P4 Ps P4 Ps
Undifferentiated          
ASC clone B1 9 17a 10 20c 15 45a 20 8a
  B2 7 14a 15 18ns 30 25ns 27 26ns
  B3 24 24ns 29 23ns 50 75a 19 19ns
Differentiated          
ASC clone B1 13 13ns 5 33a 12 13ns 17 11ns
  B2 4 17a 17 25c 22 25ns 29 24ns
  B3 22 38a 17 22ns 50 70b 18 14ns
  1. Chi-square tests: a P < 0.001; b P < 0.005; c P < 0.05; ns non-significant.