Figure 9
From: Optical biosensor differentiates signaling of endogenous PAR1 and PAR2 in A431 cells

The effect of preceding EGF stimulation on PAR signaling. (a) The Ca2+ mobilization. (b, c) The DMR signals. The ligands were EGF (100 nM), trypsin (100 nM), and thrombin (40 unit/ml). The cell responses with the pre-treatment with the HBSS only were also included as control.