Figure 4From: Intracellular mediators of transforming growth factor β superfamily signaling localize to endosomes in chicken embryo and mouse lenses in vivoLocalization of pSmad1 and pSmad2 on late endosomes in P3 mouse lens cells. A. Rab7 (red), pSmad1 (green), TOTO-1 (blue). B. Rab7 (red), pSmad2 (green), TOTO-1 (blue). Both pSmad1 and pSmad2 co-localize with Rab7 on a small number of cytoplasmic vesicles. Nuclear staining for pSmad1 and pSmad2 is mostly obscured by the strong fluorescence of the nucleic acid stain, TOTO-1.Back to article page