Figure 3From: Interleukin-10 inhibits osteoclastogenesis by reducing NFATc1 expression and preventing its translocation to the nucleusIL-10 reduces NFATc1 immunostaining intensity and nuclear translocation. NFATc1 staining was noted in the cytoplasm and nuclei of RANKL treated RAW264.7 cells (B and C), whereas only weak cytoplasmic staining was observed in RANKL + IL-10 treated cells (D.) No staining was noted in control cultures (A). Photographs taken at a magnification of × 400 A, B, D and ×1000 C.Back to article page