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Figure 6 | BMC Cell Biology

Figure 6

From: Regulation of tight junction assembly and epithelial morphogenesis by the heat shock protein Apg-2

Figure 6

Apg-2 depletion inhibits the formation of regular cysts in 3-D cultures. Control and Apg-2 RNAi cell lines were cultured without or with tetracycline in collagen/matrigel gels. The cells were regularly inspected by phase contrast microscopy to monitor cyst and lumen formation. The shown images were taken 7 days after the cultures had been started. Note, most cysts formed by Apg-2 depleted cells had an irregular shape and lacked a lumen.

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