Figure 1
Alignments of HCCR-1 with its homologs. (A) Alignment of HCCR-1 with Human LETM1 protein (gi18204589 ref AAH21208). Identities are highlighted in black and conserved substitutions by gray. (B) Schematic alignment shows the LETM1 domain structure. Analysis using Pfam revealed sequence similarity with the LETM1 domains. Scale is lengths proportional to their molecular masses. The locations of putative LETM domains are indicated by blank boxes. Homo sapiens gi18204589 ref AAH21208; Homo sapiens (HCCR-1) gi13624098 ref AAK34885; Mus musculus gi33416955 ref AAH55685; Drosophila melanogaster gi21626751 ref AAM68317; Drosophila melanogaster gi1749774 ref CAA71125; Molgula oculata, gi308969 ref AAC37181; Caenorhabditis elegans, gi17561658 ref NP_506382; Saccharomyces cerevisiae, gi6324546 ref NP_014615; Saccharomyces cerevisiae, gi1762146 ref AAB70096; Ashbya gossypii gi44980464 ref AAS50397; Ashbya gossypii, gi44980448 ref AAS50381; Neurospora crassa gi32420419 ref XP_330653; Arabidopsis thaliana, gi42562974 ref NP_176732.