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Table 1 Prediction of mitochondrial targeting of HCCR-1 and LETM1 domain-containing proteins.

From: HCCR-1, a novel oncogene, encodes a mitochondrial outer membrane protein and suppresses the UVC-induced apoptosis

   TargetP Predotar
   Score RC Score
Human AAH21208 0.882 2 0.74
  AAK34885 0.898 1 0.39
Mouse AAH55685 0.442 4 0.04
Fly AAM68317 0.932 2 0.04
  CAA71125 0.861 2 0.72
Squirt AAC37181 0.670 4 0.68
Worm NP_506382 0.943 2 0.84
Fungi NP_014615 0.924 1 0.75
  AAB70096 0.822 3 0.78
  AAS50397 0.934 1 0.85
  AAS50381 0.920 1 0.81
  XP_330653 0.798 2 0.10
Plant NP_176732 0.634 4 0.09
  1. Mitochondrial targeting sequences were detected by TargetP version 1.1 [16] and Predotar version 1.03 [17]. TargetP calculates relative for mitochondrial localization. The reliability classes (RC) of TargetP provide a score from 1 to 5, where 1 indicates the strongest prediction. Predotar provides a probability estimate as to whether the sequence contains a mitochondrial targeting sequence. Proteins with scores above 0.5 are very probably targeted to the mitochondria.