Figure 8

Tobacco smoking increases the in vivo MMP-9 burden. Total MMP-9 concentrations in the serum of smokers (n = 19) and non-smokers (n = 20) matched for age and gender were measured by ELISA. Circulating total MMP-9 concentrations are significantly increased in smokers compared to non-smokers (* p < 0.05). Error bars represent the interquartile range.