Disruption of Four Kinesin Genes in Dictyostelium

Table 1 MT Array Morphology in Interphase Cells

Cell-type	Radial MT	Comet-Tail MT	Comets (%)
AX-2 Control	588	19	3.1%
380 K	60	279	82.3%
kif8 ^-	461	1	0%
kif8^-/380 K	451	0	0%
kif10 ^-	583	12	2.0%
kif10^-/380 K	475	23	4.6%
kif11 ^-	212	26	10.9%
kif11^-/380 K	127	84	39.8%
kif4 ^-	189	9	4%
kif4^-/380 K	68	84	55%

Numbers represent individual fixed cells, either containing a normal, radial interphase microtubule array (Radial MT), or a mutant comet-like microtubule array (Comet-Tail MT) resulting from dynein motor overexpression (380 K) in different control or kinesin null cell stains. % Comet refers to the percentage of total cells that showed the distinctive mutant phenotype.

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