Table 1 Expression patterns of FUS, EWS and TAF15 in human tissues by TMA immunohistochemistry analysis
FUS | EWS | TAF15 | |||||
|---|---|---|---|---|---|---|---|
Organ | Tissue/Cell type | Nuclear | Cytoplasmic | Nuclear | Cytoplasmic | Nuclear | Cytoplasmic |
Adrenal gland | Parenchymal cells | +++ | +++ | +++ | - | +++ | +++ |
Appendix | Appendix smooth muscle | +++ | +++ | +++ | - | +++ | +++ |
Brain | |||||||
- white matter | Glial cells | +++ | - | +++ | - | +++ | - |
- grey matter | Neurons | +++ | + | +++ | - | +++ | + |
Breast | Glandular epithelium | +++ | +++ | +++ | - | +++ | +++ |
Myoepithelial cells | +++ | +++ | ++ | - | +++ | +++ | |
Endothelium, capillaries | +++ | ++ | +++ | - | +++ | +++ | |
Adipocytes | +++ | - | +++ | - | +++ | - | |
Colon & Rectum | Surface epithelium | +++ | +++ | ++ | - | +++ | +++ |
Crypt epithelium | +++ | +++ | ++ | - | +++ | +++ | |
Malt tissue, germinal centre | +++ | - | +++ | - | +++ | - | |
Malt tissue, mantle zone | +++ | - | +++ | - | ++ | - | |
Duodenum | Enterocytes, villus epithelium | +++ | +++ | ++ | - | +++ | +++ |
Enterocytes, crypt epithelium | +++ | +++ | ++ | - | +++ | +++ | |
Ganglion cells | +++ | +++ | +++ | - | +++ | +++ | |
Endometrium | |||||||
- proliferative | Glandular epithelium | +++ | +++ | +++ | - | +++ | +++ |
Stromal cells | +++ | - | ++ | - | +++ | - | |
- secretory | Glandular epithelium | +++ | +++ | +++ | - | +++ | +++ |
Stromal cells | ++ | - | ++ | - | ++ | - | |
Esophagus | Squamous epithelium, suprabasal | +++ | +++ | +++ | - | +++ | +++ |
Squamous epithelium, basal | ++ | +++ | + | - | ++ | +++ | |
Endothelium, medium-sized arteries | +++ | + | +++ | - | +++ | ++ | |
Smooth muscle cells | +++ | +++ | +++ | - | +++ | +++ | |
Gallbladder | Mucosal epithelium | +++ | +++ | +++ | +++ | +++ | +++ |
Smooth muscle cells | +++ | +++ | +++ | - | +++ | +++ | |
Heart | Cardiac muscle cells | - | - | - | - | - | - |
Cardiac endothelium | - | - | ++ | - | - | - | |
Kidney | Glomeruli | ++ | - | ++ | - | ++ | - |
Proximal tubuli | +++ | +++ | +++ | +++ | +++ | +++ | |
Distal tubuli | +++ | +++ | +++ | +++ | +++ | +++ | |
Liver | Hepatocytes | - | +++ | ++ | +++ | - | +++ |
Bile duct epithelium | +++ | +++ | +++ | +++ | +++ | +++ | |
Lung & Bronchus | Respiratory epithelium | +++ | +++ | +++ | - | +++ | +++ |
Glandular epithelium | +++ | +++ | +++ | - | +++ | +++ | |
Pneumocytes | ++ | - | ++ | - | ++ | + | |
Chondrocytes | +++ | - | ++ | - | ++ | - | |
Endothelium, capillaries | +++ | - | +++ | - | +++ | - | |
Muscle artery, endothelial cells | +++ | - | +++ | - | +++ | - | |
Muscle artery, smooth muscle | +++ | +++ | +++ | - | +++ | +++ | |
Lymph node | Germinal centre | ++ | - | ++ | - | ++ | - |
Mantle zone | ++ | - | ++ | - | ++ | - | |
Myometrium | Smooth muscle cells | + | - | + | - | + | - |
Nasal mucosa | Respiratory epithelium | +++ | ++ | ++ | - | +++ | ++ |
Glandular epithelium | +++ | +++ | +++ | - | +++ | +++ | |
Ovary | Follicular epithelium | +++ | +++ | ++ | - | +++ | +++ |
Ovarial stromal cells | +++ | - | +++ | - | +++ | - | |
Pancreas | Exocrine glands | +++ | +++ | +++ | - | +++ | +++ |
Duct epithelium | +++ | +++ | +++ | - | +++ | +++ | |
Endocrine cells | +++ | +++ | +++ | +++ | +++ | +++ | |
Placenta | Syncytiotrophoblasts | ++ | ++ | + | + | ++ | +++ |
Cytotrophoblasts | +++ | + | ++ | + | +++ | + | |
Prostate | Prostate epithelium | + | + | ++ | + | ++ | + |
Basal cells | +++ | - | +++ | - | ++ | - | |
Salivary gland | Serous cells | +++ | +++ | +++ | ++ | +++ | +++ |
Mucous cells | +++ | + | ++ | - | +++ | + | |
Intercalated/striated ducts | +++ | +++ | +++ | +++ | +++ | +++ | |
Myoepithelium | +++ | - | +++ | - | +++ | - | |
Salpinx | Glandular epithelium | +++ | +++ | +++ | - | +++ | +++ |
Seminal vesicle | Epithelium | +++ | +++ | +++ | +++ | +++ | +++ |
Skeletal muscle | Skeletal muscle fibers | ++ | - | ++ | - | +++ | - |
Skin & Subcutis | Keratinocytes | +++ | +++ | +++ | - | +++ | +++ |
Melanocytes | - | - | - | - | - | - | |
Fibroblasts | +++ | - | +++ | - | +++ | - | |
Ecrine epithelium, sweat gland | +++ | +++ | ++ | - | +++ | +++ | |
Endothelium, capillaries | +++ | - | +++ | - | +++ | - | |
Adipocytes | +++ | - | ++ | - | ++ | - | |
Spleen | Lymphocytes, red and white pulp | ++ | - | ++ | - | + | - |
Stomach | |||||||
- body | Surface & foveolar epithelium | +++ | +++ | +++ | - | +++ | +++ |
Specialized glandular epithelium | + | +++ | + | +++ | + | +++ | |
- antrum | Surface & foveolar epithelium | +++ | +++ | ++ | - | +++ | +++ |
Specialized glandular epithelium | +++ | +++ | ++ | - | +++ | ++ | |
- smooth muscle | Smooth muscle cells | +++ | - | +++ | - | +++ | - |
Small bowel | Enterocytes, villus epithelium | +++ | +++ | ++ | - | +++ | +++ |
Enterocytes, crypt epithelium | +++ | +++ | ++ | - | +++ | +++ | |
Ganglion cells | +++ | +++ | +++ | +++ | +++ | +++ | |
Testis | Germinal epithelium | +++ | - | +++ | - | +++ | - |
Leydig intestitial cells | ++ | ++ | ++ | - | ++ | +++ | |
Spermatides | + | - | + | - | ++ | - | |
Thymus | T-lymphocytes | ++ | - | ++ | - | ++ | - |
Epithelium | +++ | + | +++ | - | +++ | +++ | |
Thyroid | Follicular epithelium | +++ | +++ | ++ | - | +++ | +++ |
Tonsil | Squamous cell epithelium | +++ | +++ | +++ | - | +++ | +++ |
Lymphocytes | +++ | - | +++ | - | +++ | - | |
Umbilical cord | Stromal cells | +++ | ++ | ++ | - | +++ | ++ |
Urinary bladder | Urothelium | +++ | +++ | +++ | - | +++ | +++ |
Uterine cervix | Squamous epithelium, basal | +++ | +++ | ++ | - | +++ | +++ |
Squamous epithelium, suprabasal | +++ | +++ | +++ | - | +++ | +++ | |