Figure 7From: The lateral mobility of cell adhesion molecules is highly restricted at septate junctions in DrosophilaRole of the cytoplasmic region in the lateral mobility of paranodin analyzed by FRAP. (A) Images of neuroblastoma N2a cells co-transfected with paranodin-Δcyto (pndΔcyto) and contactin showing an example of a FRAP sequence. Bar: 5 μm. Kinetics of fluorescence recovery of GFP-tagged paranodin (B) and paranodinΔcyto (C). Data are normalized to yield an intensity of zero immediately after photobleaching and represents the average of 8 individual traces (mean ± SEM). Deletion of the cytoplasmic tail of paranodin significantly (P < 0.05) increased the mobile fraction of paranodin-GFP as assessed using ANOVA.Back to article page