TY - JOUR AU - Hemsell, D. L. AU - Grodin, J. AU - Breuner, P. F. PY - 1974 DA - 1974// TI - Plasma precursors of estrogen. II. Correlation of the extent of conversion of plasma androstenedione to estrone with age JO - J Clin Endocrinol Metab VL - 38 UR - https://doi.org/10.1210/jcem-38-3-476 DO - 10.1210/jcem-38-3-476 ID - Hemsell1974 ER - TY - JOUR AU - Ackerman, G. E. AU - Smith, M. E. AU - Mendelson, C. R. AU - MacDonald, P. C. AU - Simpson, E. R. PY - 1981 DA - 1981// TI - Aromatization of Androstenedione by Human Adipose Tissue Stromal Cells in Monolayer Culture JO - J Clin Endocrinol Metab VL - 53 UR - https://doi.org/10.1210/jcem-53-2-412 DO - 10.1210/jcem-53-2-412 ID - Ackerman1981 ER - TY - JOUR AU - Miller, W. R. AU - Anderson, T. J. AU - Jack, W. J. L. PY - 1990 DA - 1990// TI - Relationship Between Tumor Aromatase Activity, Tumor Characteristics and Response to Therapy JO - J Steroid Biochem Mol Biol VL - 37 ID - Miller1990 ER - TY - JOUR AU - Levenson, A. S. AU - Jordan, V. C. PY - 1999 DA - 1999// TI - Selective oestrogen receptor modulation: molecular pharmacology for the millennium JO - Eur J Cancer VL - 35 UR - https://doi.org/10.1016/S0959-8049(99)00183-5 DO - 10.1016/S0959-8049(99)00183-5 ID - Levenson1999 ER - TY - JOUR AU - Ali, S. AU - Coombes, R. C. PY - 2002 DA - 2002// TI - Endocrine-responsive cancer and strategies for combating resistance JO - Nat Rev Cancer VL - 2 UR - https://doi.org/10.1038/nrc721 DO - 10.1038/nrc721 ID - Ali2002 ER - TY - JOUR AU - Schafer, J. M. AU - Bentrem, D. J. AU - Takei, H. AU - Gajdos, C. AU - Badve, S. AU - Jordan, V. C. PY - 2003 DA - 2003// TI - A mechanism of drug resistance to tamoxifen in breast cancer JO - J Steroid Biochem Mol Biol VL - 83 UR - https://doi.org/10.1016/S0960-0760(02)00251-0 DO - 10.1016/S0960-0760(02)00251-0 ID - Schafer2003 ER - TY - JOUR AU - Nicholson, R. I. AU - Hutcheson, I. R. AU - Hiscox, S. E. AU - Knowlden, J. M. AU - Giles, M. AU - Barrow, D. AU - Gee, J. M. W. PY - 2005 DA - 2005// TI - Growth factor signalling and resistance to selective oestrogen receptor modulators and pure anti-oestrogens: the use of antigrowth factor therapies to treat or delay endocrine resistance in breast cancer JO - Endocr Relat Cancer VL - 12 UR - https://doi.org/10.1677/erc.1.00991 DO - 10.1677/erc.1.00991 ID - Nicholson2005 ER - TY - JOUR AU - Thuerlimann, B. AU - Koeberle, D. AU - Senn, H. PY - 2007 DA - 2007// TI - Guidelines for the adjuvant treatment of postmenopausal women with endocrine-responsive breast cancer: Past, present and future recommendations JO - Eur J Cancer VL - 43 UR - https://doi.org/10.1016/j.ejca.2006.09.003 DO - 10.1016/j.ejca.2006.09.003 ID - Thuerlimann2007 ER - TY - JOUR AU - Perez, E. A. PY - 2006 DA - 2006// TI - Appraising Adjuvant Aromatase Inhibitor Therapy JO - Oncologist VL - 11 UR - https://doi.org/10.1634/theoncologist.11-10-1058 DO - 10.1634/theoncologist.11-10-1058 ID - Perez2006 ER - TY - JOUR AU - Jordan, V. C. AU - Brodie, A. PY - 2007 DA - 2007// TI - Development and evolution of therapies targeted to the estrogen receptor for the treatment and prevention of breast cancer JO - Steroids VL - 72 UR - https://doi.org/10.1016/j.steroids.2006.10.009 DO - 10.1016/j.steroids.2006.10.009 ID - Jordan2007 ER - TY - JOUR AU - Geisler, J. PY - 2002 DA - 2002// TI - Influence of letrozole and anastrozole on total body aromatization and plasma estrogen levels in postmenopausal breast cancer patients evaluated in a randomized, cross-over study JO - J Clin Oncol VL - 20 UR - https://doi.org/10.1200/JCO.20.3.751 DO - 10.1200/JCO.20.3.751 ID - Geisler2002 ER - TY - JOUR AU - Johannessen, D. C. AU - Engan, T. AU - Di Salle, E. AU - Zurlo, M. G. AU - Paolini, J. AU - Ornati, G. AU - Piscitelli, G. AU - Kvinnsland, S. AU - Lonning, P. E. PY - 1997 DA - 1997// TI - Endocrine and clinical effects of exemestane (PNU 155971), a novel steroidal aromatase inhibitor, in postmenopausal breast cancer patients: a phase I study JO - Clin Cancer Res VL - 3 ID - Johannessen1997 ER - TY - JOUR AU - Truchet, I. AU - Jozan, S. AU - Guerrin, M. AU - Mazzolini, L. AU - Vidal, S. AU - Valette, A. PY - 2000 DA - 2000// TI - Interconnections between E2-dependent regulation of cell cycle progression and apoptosis in MCF-7 tumors growing on nude mice JO - Exp Cell Res VL - 254 UR - https://doi.org/10.1006/excr.1999.4756 DO - 10.1006/excr.1999.4756 ID - Truchet2000 ER - TY - JOUR AU - Gompel, A. AU - Somai, S. AU - Chaouat, M. AU - Kazem, A. AU - Kloosterboer, H. J. AU - Beusman, I. AU - Forgez, P. AU - Mimoun, M. AU - Rostene, W. PY - 2000 DA - 2000// TI - Hormonal regulation of apoptosis in breast cells and tissues JO - Steroids VL - 65 UR - https://doi.org/10.1016/S0039-128X(00)00172-0 DO - 10.1016/S0039-128X(00)00172-0 ID - Gompel2000 ER - TY - JOUR AU - Green, S. J. PY - 1990 DA - 1990// TI - Steroid receptors and new (anti-) steroidal agents: modulation of estrogen receptor activity by estrogens and anti-estrogens JO - J Steroid Biochem Mol Biol VL - 37 UR - https://doi.org/10.1016/0960-0760(90)90415-H DO - 10.1016/0960-0760(90)90415-H ID - Green1990 ER - TY - JOUR AU - Lippman, M. E. AU - Dickson, R. B. AU - Kasid, A. AU - Gelmann, E. AU - Davidson, N. AU - McManaway, M. AU - Huff, K. AU - Bronzert, D. AU - Bates, S. AU - Swain, S. PY - 1986 DA - 1986// TI - Autocrine and paracrine growth regulation of human breast cancer JO - J Steroid Biochem VL - 24 UR - https://doi.org/10.1016/0022-4731(86)90044-0 DO - 10.1016/0022-4731(86)90044-0 ID - Lippman1986 ER - TY - JOUR AU - Bates, S. E. AU - Davidson, N. E. AU - Valverius, E. M. AU - Freter, C. E. AU - Dickson, R. B. AU - Tam, J. P. AU - Kudlow, J. E. AU - Lippman, M. E. AU - Salomon, D. S. PY - 1988 DA - 1988// TI - Expression of transforming growth factor alpha and its messenger ribonucleic acid in human breast cancer: its regulation by estrogen and its possible functional significance JO - Mol Endocrinol VL - 2 UR - https://doi.org/10.1210/mend-2-6-543 DO - 10.1210/mend-2-6-543 ID - Bates1988 ER - TY - JOUR AU - Prall, O. W. AU - Sarcevic, B. AU - Musgrove, E. A. AU - Watts, C. K. AU - Sutherland, R. L. PY - 1997 DA - 1997// TI - Estrogen-induced activation of Cdk4 and Cdk2 during G1-S phase progression is accompanied by increased cyclin D1 expression and decreased cyclin-dependent kinase inhibitor association with cyclin E-Cdk2 JO - J Biol Chem VL - 272 UR - https://doi.org/10.1074/jbc.272.16.10882 DO - 10.1074/jbc.272.16.10882 ID - Prall1997 ER - TY - JOUR AU - Doisneau-Sixou, S. F. AU - Sergio, C. M. AU - Carroll, J. S. AU - Hui, R. AU - Musgrove, E. A. AU - Sutherland, R. L. PY - 2003 DA - 2003// TI - Estrogen and anti-estrogen regulation of cell cycle progression in breast cancer cells JO - Endocr Relat Cancer VL - 10 UR - https://doi.org/10.1677/erc.0.0100179 DO - 10.1677/erc.0.0100179 ID - Doisneau-Sixou2003 ER - TY - JOUR AU - Gross, J. M. AU - Yee, D. PY - 2003 DA - 2003// TI - The type-1 insulin-like growth factor receptor tyrosine kinase and breast cancer: biology and therapeutic relevance JO - Cancer Metastasis Rev VL - 22 UR - https://doi.org/10.1023/A:1023720928680 DO - 10.1023/A:1023720928680 ID - Gross2003 ER - TY - JOUR AU - Nicholson, R. I. AU - McClelland, R. A. AU - Gee, J. M. AU - Manning, D. L. AU - Cannon, P. AU - Robertson, J. F. AU - Ellis, I. O. AU - Blamey, R. W. PY - 1994 DA - 1994// TI - Epidermal growth factor receptor expression in breast cancer: association with response to endocrine therapy JO - Breast Cancer Res Treat VL - 29 UR - https://doi.org/10.1007/BF00666187 DO - 10.1007/BF00666187 ID - Nicholson1994 ER - TY - JOUR AU - Detre, S. AU - Salter, J. AU - Barnes, D. M. AU - Riddler, S. AU - Hills, M. AU - Johnston, S. R. AU - Gillett, C. AU - A'Hern, R. AU - Dowsett, M. PY - 1999 DA - 1999// TI - Time-related effects of estrogen withdrawal on proliferation- and cell death-related events in MCF-7 xenografts JO - Int J Cancer VL - 81 UR - https://doi.org/3.0.CO;2-S DO - 3.0.CO;2-S ID - Detre1999 ER - TY - JOUR AU - Siamak, S. AU - Fatemeh, K. PY - 2003 DA - 2003// TI - Biochemical studies of apoptosis induced by tamoxifen in estrogen receptor positice and negative breast cancer cell lines JO - Clinical Biochemistry VL - 36 UR - https://doi.org/10.1016/S0009-9120(03)00007-9 DO - 10.1016/S0009-9120(03)00007-9 ID - Siamak2003 ER - TY - JOUR AU - Mandlekar, S. AU - Kong, A. N. T. PY - 2001 DA - 2001// TI - Mechanisms of tamoxifen-induced apoptosis JO - Apoptosis VL - 6 UR - https://doi.org/10.1023/A:1012437607881 DO - 10.1023/A:1012437607881 ID - Mandlekar2001 ER - TY - JOUR AU - Obrero, M. AU - Yu, D. V. AU - Shapiro, D. J. PY - 2002 DA - 2002// TI - Estrogen receptor-dependent and estrogen receptor-independent pathways for tamoxifen and 4-hydroxytamoxifen-induced programmed cell death JO - The Journal of Biological Chemistry VL - 277 UR - https://doi.org/10.1074/jbc.M208092200 DO - 10.1074/jbc.M208092200 ID - Obrero2002 ER - TY - JOUR AU - Zhang, G. J. AU - Kimijima, I. AU - Onda, M. AU - Kanno, M. AU - Sato, H. AU - Watanabe, T. AU - Tsuchiya, A. AU - Abe, R. AU - Takenoshita, S. PY - 1999 DA - 1999// TI - Tamoxifen-induced apoptosis in breast cancer cells relates to down-regulation of bcl-2, but not bax and bcl-X(L), without alteration of p53 protein levels JO - Clin Cancer Res VL - 5 ID - Zhang1999 ER - TY - JOUR AU - Lim, K. B. AU - Ng, C. Y. AU - Ong, C. K. AU - Ong, C. S. AU - Tran, E. AU - Nguyen, T. T. AU - Chan, G. M. AU - Huynh, H. PY - 2001 DA - 2001// TI - Induction of apoptosis in mammary gland by a pure anti-estrogen ICI 182780 JO - Breast Cancer Res Treat VL - 68 UR - https://doi.org/10.1023/A:1011929222555 DO - 10.1023/A:1011929222555 ID - Lim2001 ER - TY - JOUR AU - Thiantanawat, A. AU - Long, B. J. AU - Brodie, A. M. PY - 2003 DA - 2003// TI - Signaling pathways of apoptosis activated by aromatase inhibitors and antiestrogens JO - Cancer Res VL - 63 ID - Thiantanawat2003 ER - TY - JOUR AU - Cepa, M. AU - Tavares da Silva, E. AU - Correia-da-Silva, G. AU - Roleira, F. AU - Teixeira, N. A. PY - 2005 DA - 2005// TI - Structure-activity relationships of new A, D-ring modified steroids as aromatase inhibitors. Design, synthesis and biological activity evaluation JO - J Med Chem VL - 48 UR - https://doi.org/10.1021/jm050129p DO - 10.1021/jm050129p ID - Cepa2005 ER - TY - JOUR AU - Tavares da Silva, E. J. AU - Roleira, F. M. AU - Sa e Melo, M. L. AU - Neves, A. S. AU - Paixao, J. A. AU - Almeida, M. J. AU - Silva, M. R. AU - Andrade, L. C. PY - 2002 DA - 2002// TI - X-ray and deuterium labeling studies on the abnormal ring cleavages of a 5 beta-epoxide precursor of formestane JO - Steroids VL - 67 UR - https://doi.org/10.1016/S0039-128X(01)00164-7 DO - 10.1016/S0039-128X(01)00164-7 ID - Tavares da Silva2002 ER - TY - JOUR AU - Berthois, Y. AU - Katzenellenbogen, J. A. AU - Katzenellenbogen, B. S. PY - 1986 DA - 1986// TI - Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture JO - Proc Natl Acad Sci USA VL - 83 UR - https://doi.org/10.1073/pnas.83.8.2496 DO - 10.1073/pnas.83.8.2496 ID - Berthois1986 ER - TY - JOUR AU - Zhou, D. J. AU - Pompon, D. AU - Chen, S. A. PY - 1990 DA - 1990// TI - Stable expression of human aromatase complementary DNA in mammalian cells: a useful system for aromatase inhibitor screening JO - Cancer Res VL - 50 ID - Zhou1990 ER - TY - CHAP AU - Cepa, M. AU - Correia-da-Silva, G. AU - Tavares da Silva, E. AU - Roleira, F. M. AU - Hong, Y. AU - Chen, S. AU - Teixeira, N. A. PY - 2008 DA - 2008// TI - Molecular mechanisms of aromatase inhibition by new A, D-ring modified steroids BT - Biol Chem ID - Cepa2008 ER - TY - JOUR AU - Liu, Z. AU - Zhu, B. T. PY - 2004 DA - 2004// TI - Concentration-dependent mitogenic an aniproliferative action of 2-methoxyestradiol in estrogen receptor-positive human breast cancer cells JO - J Steroid Biochem Mol Biol VL - 88 UR - https://doi.org/10.1016/j.jsbmb.2003.12.003 DO - 10.1016/j.jsbmb.2003.12.003 ID - Liu2004 ER - TY - JOUR AU - Bowers, J. L. AU - Tyulmenkov, V. V. AU - Jernigan, S. C. AU - Klinge, C. M. PY - 2000 DA - 2000// TI - Resveratrol acts as a mixed agonist/antagonist for estrogen receptors alpha and beta JO - Endocrinology VL - 141 ID - Bowers2000 ER - TY - JOUR AU - Gehm, B. D. AU - McAndrews, J. M. AU - Chien, P. Y. AU - Jameson, J. L. PY - 1997 DA - 1997// TI - Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor JO - Proc Natl Acad Sci USA VL - 94 UR - https://doi.org/10.1073/pnas.94.25.14138 DO - 10.1073/pnas.94.25.14138 ID - Gehm1997 ER - TY - JOUR AU - Sutherland, T. E. AU - Schuliga, M. AU - Harris, T. AU - Eckhardt, B. L. AU - Anderson, R. L. AU - Quan, L. AU - Stewart, A. G. PY - 2005 DA - 2005// TI - 2-methoxyestradiol is an estrogen receptor agonist that supports tumor growth in murine xenograft models of breast cancer JO - Clin Cancer Res VL - 11 UR - https://doi.org/10.1158/1078-0432.CCR-04-1789 DO - 10.1158/1078-0432.CCR-04-1789 ID - Sutherland2005 ER - TY - JOUR AU - Jänicke, R. U. AU - Sprengart, M. L. AU - Wati, W. R. AU - Porter, A. PY - 1998 DA - 1998// TI - Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis JO - J Biol Chem VL - 273 UR - https://doi.org/10.1074/jbc.273.16.9357 DO - 10.1074/jbc.273.16.9357 ID - Jänicke1998 ER - TY - JOUR AU - Mooney, L. M. AU - Al-Sakkaf, K. A. AU - Brown, B. L. AU - Dobson, P. R. M. PY - 2002 DA - 2002// TI - Apoptotic mechanisms in T47D and MCF-7 human breast cancer cells JO - Br J Cancer VL - 87 UR - https://doi.org/10.1038/sj.bjc.6600541 DO - 10.1038/sj.bjc.6600541 ID - Mooney2002 ER - TY - JOUR AU - Xue, L. Y. AU - Chiu, S. M. AU - Oleinick, N. L. PY - 2003 DA - 2003// TI - Staurosporine-induced deathof MCF-7 human breast cancer cells: a distinction between caspase-3-dependent steps of apoptosis and the critical lethal lesions JO - Exp Cell Res VL - 283 UR - https://doi.org/10.1016/S0014-4827(02)00032-0 DO - 10.1016/S0014-4827(02)00032-0 ID - Xue2003 ER - TY - JOUR AU - Petroski, G. AU - Zahuczky, G. AU - Májai, G. AU - Fésüs, L. PY - 2007 DA - 2007// TI - Phagocytosis of cells dying through autophagy evokes a por-inflamatory response in macrophages JO - Autophagy VL - 3 ID - Petroski2007 ER - TY - JOUR AU - Madden, D. T. AU - Egger, L. AU - Bredesen, D. E. PY - 2007 DA - 2007// TI - A calpain-like protease inhibits autophagic cell death JO - Autophagy VL - 3 ID - Madden2007 ER - TY - JOUR AU - Ondroušková, E. AU - Souek, K. AU - Horváth, V. AU - Smarda, J. PY - 2007 DA - 2007// TI - Alternative pathways of programmed cell death are activated in cells with defective caspase-dependent apoptosis JO - Leuk Res VL - 32 UR - https://doi.org/10.1016/j.leukres.2007.05.012 DO - 10.1016/j.leukres.2007.05.012 ID - Ondroušková2007 ER - TY - JOUR AU - Motyl, T. AU - Gajkowska, J. AU - Gajewska, M. AU - Lamparska-Przybysz, M. PY - 2006 DA - 2006// TI - Apoptosis and autophagy in mammary gland remodeling and breast cancer therapy JO - Journal of Physiology and Pharmacology VL - 57 ID - Motyl2006 ER - TY - JOUR AU - Jia, L. AU - Dourmashkin, R. R. AU - Allen, P. D. AU - Gray, A. B. AU - Newland, A. C. AU - Kelsey, S. M. PY - 1997 DA - 1997// TI - Inhibition of autophagy abrogates tumor necrosis factor alpha induced apoptosis in human T-lymphoblastic leukaemic cells JO - Br J Haematol VL - 98 UR - https://doi.org/10.1046/j.1365-2141.1997.2623081.x DO - 10.1046/j.1365-2141.1997.2623081.x ID - Jia1997 ER - TY - JOUR AU - Cui, Q. AU - Tashiro, S. AU - Onodera, S. AU - Minami, M. AU - Ikejima, T. PY - 2007 DA - 2007// TI - Autophagy preceded apoptosis in oridonin-treated human breast cancer MCF-7 cells JO - Biol Pharm Bull VL - 30 UR - https://doi.org/10.1248/bpb.30.859 DO - 10.1248/bpb.30.859 ID - Cui2007 ER - TY - JOUR AU - Jia, L. AU - Dourmashkin, R. R. AU - Newland, A. C. AU - Kelsey, S. M. PY - 1997 DA - 1997// TI - Mitochondrial ultracondensation, but not swelling, is involved in TNF alpha-induced apoptosis in human T-lymphoblastic leukaemic cells JO - Leuk Res VL - 21 UR - https://doi.org/10.1016/S0145-2126(97)00078-7 DO - 10.1016/S0145-2126(97)00078-7 ID - Jia1997 ER - TY - JOUR AU - Valentim, L. AU - Laurence, K. M. AU - Townsend, P. A. AU - Carroll, C. J. AU - Soond, S. AU - Scarabelli, T. M. AU - Knight, R. A. AU - Latchman, D. S. AU - Stephanou, A. PY - 2006 DA - 2006// TI - Urocortin inhibits Beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury JO - J Mol Cell Cardiol VL - 40 UR - https://doi.org/10.1016/j.yjmcc.2006.03.428 DO - 10.1016/j.yjmcc.2006.03.428 ID - Valentim2006 ER - TY - JOUR AU - Bursch, W. AU - Ellinger, A. AU - Kienzl, H. AU - Torok, L. AU - Pandey, S. AU - Sikorska, M. AU - Walker, R. AU - Hermann, R. S. PY - 1996 DA - 1996// TI - Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy JO - Carcinogenesis VL - 17 UR - https://doi.org/10.1093/carcin/17.8.1595 DO - 10.1093/carcin/17.8.1595 ID - Bursch1996 ER - TY - JOUR AU - Bursch, W. AU - Hochegger, K. AU - Torok, L. AU - Marian, B. AU - Ellinger, A. AU - Hermann, R. S. PY - 2000 DA - 2000// TI - Autophagic and apoptotic types of programmed cell death exhibit different fates of cytoskeletal filaments JO - J Cell Sci VL - 113 ID - Bursch2000 ER - TY - JOUR AU - Scarlatti, F. AU - Bauvy, C. AU - Ventruti, A. AU - Sala, G. AU - Cluzeaud, F. AU - Vandewalle, A. AU - Ghidoni, R. AU - Codogno, P. PY - 2004 DA - 2004// TI - Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1 JO - J Biol Chem VL - 278 UR - https://doi.org/10.1074/jbc.M313561200 DO - 10.1074/jbc.M313561200 ID - Scarlatti2004 ER - TY - JOUR AU - Petrovski, G. AU - Zahuczky, G. AU - Katona, K. AU - Vereb, G. AU - Martinet, W. AU - Nemes, Z. AU - Bursch, W. AU - Fésüs, L. PY - 2007 DA - 2007// TI - Clearance of dying autophagic cells of different origin by professional and non-professional phagocytes JO - Cell Death Differ VL - 14 UR - https://doi.org/10.1038/sj.cdd.4402112 DO - 10.1038/sj.cdd.4402112 ID - Petrovski2007 ER - TY - JOUR AU - Bilir, A. AU - Altinoz, M. A. AU - Erkan, M. AU - Ozmen, V. AU - Aydiner, A. PY - 2001 DA - 2001// TI - Autophagy and nuclear changes in FM3A breast tumor cells after epirrubicin, medroxyprogesterone and tamoxifen treatment in vitro JO - Pathobiology VL - 69 UR - https://doi.org/10.1159/000048766 DO - 10.1159/000048766 ID - Bilir2001 ER - TY - JOUR AU - Yan, C. H. AU - Yang, Y. P. AU - Qin, Z. H. AU - Gu, Z. L. AU - Reid, P. AU - Liang, Z. Q. PY - 2007 DA - 2007// TI - Autophagy is involved in cytotoxic effects of crotoxin in human breast cancer cell line MCF-7 cells JO - Acta Pharmacol Sin VL - 28 UR - https://doi.org/10.1111/j.1745-7254.2007.00530.x DO - 10.1111/j.1745-7254.2007.00530.x ID - Yan2007 ER -