Ultrastructural features of cell death in control MCF-7aro cells (A) and after treatment with 25 μM compound 4a (B-C) after 72 hr incubation. (A) The cytoplasm tipically shows multiple polyribosomes and numerous mitochondria. (B) The cytoplasm shows multiple autophagic vacuoles containing cytoplasmic fragments (arrows). The chromatin is irregularly condensed (arrowheads). (C) is ahigher magnification of (B).