Figure 1From: Prolonged exposure to bacterial toxins downregulated expression of toll-like receptors in mesenchymal stromal cell-derived osteoprogenitorsEffects of LPS and LTA on the proliferation of human MSCs and PBMCs. Cultured cells were incubated with either LPS (left panel) or LTA (right panel) for 3 days or 7 days. On Day 3 and Day 7, the cell proliferation responses of (A) MSCs and (B) PBMCs were assessed by XTT assay respectively. LPS and LTA did not affect the proliferation of MSCs (pooled data from three experiments, each done in triplicates) but increased proliferation of PBMCs (one representative experiment done in triplicates). The data are expressed as the relative proliferation of untreated controls, mean ± SEM. * P < 0.05; ** P < 0.01; *** P < 0.001 versus control.Back to article page