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Figure 7 | BMC Cell Biology

Figure 7

From: Phosphatidylinositol 3-kinase signaling in proliferating cells maintains an anti-apoptotic transcriptional program mediated by inhibition of FOXO and non-canonical activation of NFκB transcription factors

Figure 7

PI 3-kinase inhibition causes a decrease in RelB binding. T98G cells were either maintained in serum or treated with 50 μM LY294002 for 4 or 8 hours. Chromatin fragments were immunoprecipitated with anti-RelB antibody and quantified by real-time PCR. Data are presented as the percentage of input and are the means of 3 independent experiments ± S.E. β-globin was used as the negative control. (*) represents statistically significant loss of binding compared to the cells maintained in serum (assessed by t test).

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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