Rab27 does not regulate LPS dependent neutrophil recruitment to the lungs in vivo . Wild-type (WT) and Rab27a/b double knockout (Rab27DKO) mice were treated with PBS vehicle or LPS and 6 hours after treatment bronchoalveolar lavage (BAL) (A), lung tissue (B) and blood cells (C) were collected and total and neutrophil numbers quantified by differential staining. Error bars s.e.m. P values student’s t test. Data from PBS treated mice (n = 8 for wild-type and Rab27DKO) and LPS treated mice (n-8 for wild-type and n = 9 for Rab27DKO).