| |
BM-MSC
|
AT-MSC
|
WJ-MSC
|
|---|
|
d10
|
d21
|
d10
|
d21
|
d10
|
d21
|
|---|
|
PPARG
|
14.9 ± 2.5 a
|
32.3 ± 3.0 a
|
21.0 ± 6.4 a
|
58.3 ± 13.6 b
|
15.2 ± 8.9 a
|
29.1 ± 3.2 a
|
|
ADIPOQ
|
4,126.8 ± 3,370.2 a
|
3,994.2 ± 1,292.7 a
|
3,378.4 ± 2,243.0 a
|
423,626.8 ± 147,352.8 b
|
*
|
*
|
|
CEBPA
|
102.6 ± 14.6 a
|
89.7 ± 33.1 a
|
206.6 ± 53.9 a
|
1,271.3 ± 245.3 b
|
12.1 ± 6.6 a
|
17.3 ± 4.3 a
|
|
SOX2
|
**
|
2.5 ± 1.4 a
|
7.1 ± 0.8 a
|
4,800.8 ± 387.7 b
|
5.8 ± 3.0 a
|
3.0 ± 1.1 a
|
|
POU5F1
|
0.7 ± 0.3 a
|
0.6 ± 0.1 a
|
4.0 ± 1.0 a
|
142.5 ± 0.2 b
|
3.9 ± 2.2 a
|
0.3 ± 0.1 a
|
- ADIPOQ: adiponectin; AT-MSC: adipose tissue-derived MSC; BM-MSC: bone marrow-derived MSC; CEPBA: CCAAT/enhancer-binding protein alpha; d10: day 10; d21: day 21; MSC: mesenchymal stromal cells; POU5F1: POU domain, class 5, transcription factor 1; PPARG: peroxisome proliferator-activated receptor gamma; SOX2: SRY (Sex Determining Region Y)-Box 2; WJ-MSC: Wharton’s Jelly-derived MSC; *not detected in initial sample (d0); **not detected in that particular sample (d10 or d21).
- Negative values mean downregulation on mRNA expression when compared to non-induced cultured cells, and positive values, upregulation. Statistical significance was assessed by one-way non-parametric ANOVA followed by Bonferroni post-hoc test to compare all pairs of data for a determined gene (α = 0.05, n = 3). In a same row, a same letter means that both conditions are not significantly different; different letters (superscript letters a and b) indicate statistically different values.
