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Figure 6 | BMC Cell Biology

Figure 6

From: Hydrophobicity of protein determinants influences the recognition of substrates by EDEM1 and EDEM2 in human cells

Figure 6

Biochemical characteristics of BACE457 DHF . (A) Sequence of the C-terminal hydrophobic region of BACE457. Introduced mutations are marked in red. (B) Hydrophobicity plot for the C-terminal region (Ile414-Val434) of BACE457 and BACE457DHF. Presented graph is a fragment of the output from ProtScale [64] prepared for full-length BACE457. A sliding window of 19 AAs was used. (C) Topology prediction of BACE457 and BACE457DHF prepared by TMHMM Server v. 2.0 [66]. Graph shows the posterior probabilities of inside/outside/transmembrane helices. The red bars indicate predicted transmembrane regions, their length and posterior probabilities are indicated on X and Y axes respectively.

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