Fig. 4
From: The clustered protocadherin endolysosomal trafficking motif mediates cytoplasmic association
Internal deletions within the VCD motif affect surface trafficking. a Internal deletions within the VCD stub and location of the FLAG epitope used to detect surface delivery. b Quantification of surface delivery. Average pixel value of surface FLAG immunoreactivity for each construct was calculated from 50 cells per condition ± SEM. Significance determined by t-test. * indicates p < 0.001. c Surface labeling (red) of VCD stub GFP (green) and indicated deletions. Constructs more highly expressed on the surface resulted in more prominent filopodia (arrowheads) labeled with the FLAG antibody