Skip to main content
Fig. 3 | BMC Cell Biology

Fig. 3

From: Altered cellular localization and hemichannel activities of KID syndrome associated connexin26 I30N and D50Y mutations

Fig. 3

Fluorescent dye uptake in Cx26WT, I30N and D50Y transfected cells. a Comparison of fluorescent dye intensities in transfected cells under physiological calcium concentration. Cx26I30N and D50Y were compared with both negative control pIRES2EGFP2 and Cx26WT (*, p < 0.01). b Comparison of fluorescent dye intensities in transfected cells in divalent free medium and in the presence of 100 μM CBX, a hemichannel blocker. Cx26WT, I30N and D50Y were compared with negative control pIRES2EGFP2 (*, p < 0.01); Cx26I30N and D50Y were compared with Cx26WT (†, p < 0.01) and comparison between samples treated with or without CBX was performed (‡, p < 0.01)

Back to article page