Fig. 12
From: Spatiotemporal patterns of sortilin and SorCS2 localization during organ development
SorCS2 is expressed in striated muscle, costae, mandible and adipose tissue. Immunohistofluorescence was performed on sagittal sections (10 μm) of embryos on embryonic day E13.5, E15.5 and E17.5. a-c. SorCS2 is expressed in striated muscle at all age points, localizing both in satellite cells and in striated bands with a diminishing trend at E17.5. d-g. SorCS2 shows marked concentric expression in developing costae, as well as in the ossifying mandible. h,i. SorCS2 is also expressed in brown adipose tissue. Green channel is SorCS2 and blue channel is Hoechst nuclear stain. Scale bars = 50 μm. Ba, brown adipose tissue Cl, clavicle; Ma, mandible; Sm, striated muscle; St, sternum