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Fig. 8 | BMC Cell Biology

Fig. 8

From: Spatiotemporal patterns of sortilin and SorCS2 localization during organ development

Fig. 8

Sortilin is expressed in costae, vertebrae and brown adipose tissue. Immunohistofluorescence was performed on sagittal sections (10 μm) of embryos on embryonic day E13.5, E15.5 and E17.5. Sortilin show marked central expression in developing costae (a-c), as well as in the chondral primordium and later ossifying vertebrae (d-f). Sortilin expression is absent from brown adipose tissue until E17.5 where it is prominent (g,h). Green channel is sortilin and blue channel is Hoechst nuclear stain. Scale bars = 50 μm. Ba, brown adipose tissue; Co, costae; Ve, vertebrae

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