Skip to main content
Fig. 9 | BMC Cell Biology

Fig. 9

From: Molecular mechanisms regulating formation, trafficking and processing of annular gap junctions

Fig. 9

Gap junction plaque assembly and structure. a Photoconversion of Cx43-Dendra2 reveals accrual of newly synthesized gap junction channels (non-converted, green) along the outer edge of gap junction plaques (permanently photoconverted from green to red; shown for two gap junction plaques viewed en face/onto the plaque surface). (From ref. [73].) b Schematic model of a gap junction depicting our hypothesized plaque organization. c Cx43 gap junctions (green) colocalizing with the scaffolding protein, ZO-1 (red), generating a typical staining along the rim of gap junction plaques [130], shown in fixed endogenously Cx43 expressing primary pulmonary artery endothelial cells (PAECs). The boxed area is shown enlarged on the right. (From ref. [131])

Back to article page