Fig. 3

Mutations affecting function of HCs. Models of single Cxs chains are represented as cartoons, and colored with a blue-green gradient from the N- to the CT region, for (a) Cx26 (b) Cx32, (c) Cx43 and (d) Cx50. Positions of loss of function mutations are colored as red and gain of function mutations as yellow. The figure was generated with PyMol and edited with Gimp