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Fig. 2 | BMC Cell Biology

Fig. 2

From: Microvesicles derived from hypoxia/reoxygenation-treated human umbilical vein endothelial cells promote apoptosis and oxidative stress in H9c2 cardiomyocytes

Fig. 2

H/R-EMVs exerted cytotoxic effect on H9c2 cells. a MTT assays. H9c2 cells were treated with 10, 30, 60 μg/mL H/R-EMVs for 6 h. The viability of H9c2 cells was expressed as a percentage relative to non-H/R-EMVs-treated control cells. Control cells were considered to be 100 % viable. b LDH activity assay. H9c2 cells were treated at the concentration of 10, 30, 60 μg/mL H/R-EMVs for 6 h to detect LDH activity. *p < 0.05, ***p < 0.001 versus control; ### p < 0.001 versus H/R-EMVs 10 μg/mL; && p < 0.01, &&& p < 0.001 versus H/R-EMVs 30 μg/mL

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