Fig. 4
From: Early changes in the metabolic profile of activated CD8+ T cells
Inhibition of lactate production leads to decreased proliferation/IL-2 is necessary for lactate production. Purified CD8+ T cells were treated with OT-I tetramers for the indicated time periods. Samples were analyzed for proliferation (a) and lactate production (b) in presence of rotenone or oxamate. Samples were analyzed for lactate production in presence of IL-2 or anti-IL-2 (c). n = 3