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Fig. 1 | BMC Cell Biology

Fig. 1

From: Aneuploidy screening of embryonic stem cell clones by metaphase karyotyping and droplet digital polymerase chain reaction

Fig. 1

Contribution of euploid cells and GLT rate in all C57BL/6N-derived clones. Percentage of euploid metaphases observed by Giemsa staining metaphase spread-based karyotyping was compared to germ line efficiency obtained at ICS (left axis, grey). Number of ES mutant clones tested is indicated on the right axis (cross). Data was analysed using the Fisher Exact test and yielded a P value of 0.000806. False discovery rate (Q) calculated by the Benjamini-Hochberg procedure was 0.003224. This showed that clones with greater than 50 % euploid representation are preferable candidates for microinjection

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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