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Fig. 2 | BMC Cell Biology

Fig. 2

From: Cardiac Cx43, Cx40 and Cx45 co-assembling: involvement of connexins epitopes in formation of hemichannels and Gap junction channels

Fig. 2

connexin composition of connexons and GJCs in cells co-expressing 2 and 3 Cxs isoforms. a: homomeric connexons: double Cxs co-expression (left panel) and triple Cxs co-expression (right panel). b: examples of diverse Cxs compositions of heteromeric connexons made of 2 isoforms: double Cxs co- expression (left panel) and triple Cxs co-expression (right panel). c: examples of diverse Cxs compositions of heteromeric connexons made of 3 isoforms. The colored numbers indicate the relative amount of Cxs isoforms. d: diverse types of GJCs for a triple Cxs co-expression: homotypic (left panel), heterotypic (middle panel), and heteromeric (right panel). The numbers in frames indicate the statistical total amount of each configuration

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