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Fig. 1 | BMC Cell Biology

Fig. 1

From: Accessing gap-junction channel structure-function relationships through molecular modeling and simulations

Fig. 1

Early electron microscopy images of gap junction channels. a Cellular membrane between two rat liver cells. b Cellular membrane of rat liver cells immediately after isolation exhibiting the characteristic hexagonal pattern. c A highly magnified portion of the cellular membrane shown in Panel b. d Higher magnification and rotation of a portion of the cellular membrane shown in Panel c. e A digital zoom-in to the central yellow box denoting the extracellular portion of a hemichannel. Note the clear hexagonal symmetry. f The open/close model of a GJC proposed by Unwin and Zampighi [11]. Panels a to e, adapted from Benedetti and Emmelot [6]. Panel f, adapted from Unwin and Zampighi [11]

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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