Fig. 6

Structure of hCx26. Column (a) crystallographic structure [19]; Column (b) modeled structure with completed CL and C-terminus plus missing residues and sidechains; Column (c), modeled structure after MD simulation. Upper row, structure of the channel viewed from extracellular side. Middle row,cartoon representation of two opposing monomers in a side view, with pore-lining residues in ball & stick. Lower row, pore radius as a function of pore length. Taken from Kwon et al., [22]