TY - JOUR AU - Smith, Elizabeth R. AU - Meng, Yue AU - Moore, Robert AU - Tse, Jeffrey D. AU - Xu, Arn G. AU - Xu, Xiang-Xi PY - 2017 DA - 2017/01/14 TI - Nuclear envelope structural proteins facilitate nuclear shape changes accompanying embryonic differentiation and fidelity of gene expression JO - BMC Cell Biology SP - 8 VL - 18 IS - 1 AB - Nuclear size and shape are specific to a cell type, function, and location, and can serve as indicators of disease and development. We previously found that lamin A/C and associated nuclear envelope structural proteins were upregulated when murine embryonic stem (ES) cells differentiated to primitive endoderm cells. Here we further investigated the morphological changes of nuclei that accompany this differentiation. SN - 1471-2121 UR - https://doi.org/10.1186/s12860-017-0125-0 DO - 10.1186/s12860-017-0125-0 ID - Smith2017 ER -