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Table 1 Nuclear measurements in blastocysts. Confocal imaging analysis was used to determine the x-, y-, and z-dimensions of nuclei in E4.5 blastocysts. The volumes of the nuclei were calculated from the measurements, as described in Methods

From: Nuclear envelope structural proteins facilitate nuclear shape changes accompanying embryonic differentiation and fidelity of gene expression

Blastocyst Nuclei Oct4 + / Gata6 – ICM cells Oct4 - / Gata6 + Trophectoderm Oct4 +/− / Gata6 +Primitive endoderm
(μm) Mean ± S.D. Mean ± S.D. Mean ± S.D.
x- dimension 13.3 ± 0.27 10.98 ± 0.41 11.99 ± 0.56
y- dimension 16.8 ± 2.36 13.5 ± 0.43 12.5 ± 2.25
z- dimension 8.73 ± 1.12 8.78 ± 0.55 7.79 ± 1.51
Volume (μm3) 1001 ± 129 688 ± 73 616 ± 126