Fig. 2

BMP-12 treatment activates tenogenic pathway in hASCs. Real time PCR in human adipose stem cells (hASCs) treated or not with 100 ng/ml BMP-12 for 7 days. Results presented as fold of change in relation to the internal control samples (cells from the same donor cultured in parallel in standard growth medium). hASCs obtained from 6 independent donors were used. Col1a1- Collagen, type I, alpha 1; DCN- Decorin; RUNX- Runt-related transcription factor 2; MKX- Mohawk homeobox; SCX- Scleraxis; TNC- Tenascin; GAPDH gene was used for normalization