Fig. 7From: Impact of the MDM2 splice-variants MDM2-A, MDM2-B and MDM2-C on cytotoxic stress response in breast cancer cellsInduction of senescence. Graphs show the percentage of senescent cells after transfection with pCMV (TOPO-Control) and the splice variants, untreated (purple bars) or treated with 0.25 μM doxorubicin (green bars). Cells were analyzed by β-galactosidase assay 8 days post transfection. The experiment was repeated in triplicate with three independent transfectionsBack to article page