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Table 1 IC50 values of Cladosporol A against NC1 60 panel of human cancer cell lines of different tissue origin. Data are expressed as the mean ± SD of three similar experiments

From: Cladosporol A triggers apoptosis sensitivity by ROS-mediated autophagic flux in human breast cancer cells

IC50(μM)

S.No

MCF-7 (Breast cancer)

A549 (Lung cancer)

HCT-116 (Colon cancer)

PC-3 (Prostate cancer)

OVCAR-3 (Ovarian Cancer)

Cladosporol A

8.7 ± 0.205

11.7 ± 0.505

12 ± 0.505

15.6 ± 0.360

10.3 ± 0.556

 Paclitaxel

0.0.25 ± 0.001

0.75 ± 0.05

8.5 ± 0.620

0.48 ± 0.003

2.6 ± 0.120

 Doxorubicin

0.1 ± 0.006

0.087 ± 0.009

0.096 ± 0.005

0.05 ± 0.006

0.13 ± 0.008