Fig. 7

TGF-β production from HMFs encapsulated in mTG hydrogels. HMFs were encapsulated in compliant, moderate and stiff hydrogels and conditioned media was collected at days 1, 3, 5 and 7 of culture for quantification of secreted TGF-β. Overall, TGF-β levels increased during the culture period for HMFs encapsulated in compliant (a), moderate (b) and stiff (c) hydrogels. (d) TGF-β production was significantly greater for HMFs encapsulated in stiff hydrogels at days 5 and 7 of culture. ^* p ≤ 0.05; ^** p ≤ 0.01; ^*** p ≤ 0.001