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Fig. 11 | BMC Cell Biology

Fig. 11

From: Mannan oligosaccharide requires functional ETC and TLR for biological radiation protection to normal cells

Fig. 11

Summary of mechanism of action of MOS. Cells treated with or without MOS showed altered MMP and Enhanced ROS generation. Pre-irradiation treatment of cells with MOS specifically protected normal cells, suggesting requirement of TLR and functional integrity of ETC. MOS also found to upregulate MnSOD and Cu/ZnSOD expression and activated NFκB. All these factors might have collectively contributed towards radio-protective efficacy unveiled by MOS

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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