Fig. 3
From: Downregulation of lncRNA CCAT1 enhances 5-fluorouracil sensitivity in human colon cancer cells
Role of CCAT1 in chemosensitivity of parental or 5-FU-resistant colon cancer cell lines. a, b. qRT-PCR assay was performed to examine the expression of CCAT1 after the transfection of HCT 116 or HT-29 cells with pcDNA3.1-CCAT1 and of HCT 116/5-FU or HT-29/5-FU cells with siRNA-CCAT1. c, d. IC50 values for 5-FU in HCT 116 or HT-29 cells transfected with pcDNA3.1-CCAT1 and HCT 116/5-FU or HT-29/5-FU cells transfected with siRNA-CCAT1. **P < 0.01 compared with respective NC group