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Fig. 5 | BMC Molecular and Cell Biology

Fig. 5

From: Lamin A/C and Emerin depletion impacts chromatin organization and dynamics in the interphase nucleus

Fig. 5

Lamin A/C-Emerin co-depletion mislocalizes chromosome 17 territories. a Representative 3D-FISH images for CT7 (red) and CT17 (green) in control (untreated) cells, and single and co-depletion of Lamin A/C and Emerin. Scale bar ~ 10 μm. b-c Radial Distance (% R.D) distribution profiles for (b) CT17 and (c) CT7 in control (untreated) cells, and single and co-depletion of Lamin A/C and Emerin (X-axis: 0%: nuclear centre, 100%: nuclear periphery). Error bar: SEM, *** p < 0.001, n = number of CTs analysed, compiled data from N = 2 (N: number of independent biological replicates)

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