Fig. 4From: SAA1 increases NOX4/ROS production to promote LPS-induced inflammation in vascular smooth muscle cells through activating p38MAPK/NF-κB pathwayEffects of recombinant SAA1 protein treatment for different time points on NOX4/ROS pathway in LPS-induced VSMCs (n = 3). Notes: The levels of O2− production (a), NADPH oxidase activity (b) and NOX-4 protein (c-d) in VSMC after pre-incubation with 20 μg/ml SAA1 for different time points (0, 24, 48, 72 h) followed by the addition with 1 μg/ml LPS for 24 h. The same letters represented no significant differences, P > 0.05; and different letters indicated significant differences, P < 0.05Back to article page