Table 3 Marginal distributions (%) of amino acids by position relative to the S/T-site
Amino Acid | Eight positions to the left/right of the S/T-site for O-GalNAc glycosylated sequences | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
-8 | -7 | -6 | -5 | -4 | -3 | -2 | -1 | +1 | +2 | +3 | +4 | +5 | +6 | +7 | +8 | |
A | 7.7 | 7.2 | 7.0 | 7.2 | 6.6 | 7.0 | 9.1 | 8.5 | 7.7 | 10.2 | 7.9 | 6.8 | 8.0 | 8.2 | 7.9 | 7.8 |
C | 0.9 | 0.8 | 0.9 | 0.4 | 0.8 | 0.4 | 0.4 | 0.1 | 0.9 | 0.1 | 0.3 | 0.4 | 0.7 | 0.6 | 0.7 | 1.4 |
D | 4.3 | 4.5 | 4.1 | 3.8 | 4.1 | 3.4 | 4.2 | 1.3 | 3.9 | 4.0 | 4.3 | 3.7 | 5.2 | 4.6 | 4.6 | 5.0 |
E | 6.4 | 6.2 | 6.6 | 6.8 | 6.4 | 8.3 | 6.6 | 4.4 | 7.0 | 6.2 | 5.2 | 7.0 | 7.8 | 6.6 | 7.1 | 8.0 |
F | 2.4 | 2.4 | 2.3 | 2.2 | 2.3 | 2.4 | 2.7 | 2.8 | 1.6 | 2.0 | 2.7 | 2.0 | 2.3 | 2.3 | 2.0 | 2.2 |
G | 6.9 | 6.7 | 6.9 | 6.8 | 6.2 | 5.2 | 7.6 | 5.3 | 5.6 | 7.2 | 6.0 | 6.8 | 6.1 | 7.6 | 7.8 | 6.8 |
H | 3.6 | 3.8 | 2.9 | 4.3 | 4.5 | 3.6 | 3.6 | 4.5 | 3.8 | 4.0 | 2.8 | 3.5 | 3.5 | 3.2 | 3.4 | 3.0 |
I | 2.9 | 3.2 | 2.7 | 3.0 | 3.6 | 3.4 | 3.0 | 3.2 | 2.4 | 2.7 | 2.3 | 2.7 | 3.2 | 2.1 | 2.0 | 2.3 |
K | 5.7 | 5.4 | 5.7 | 5.8 | 5.1 | 5.6 | 5.5 | 3.3 | 4.6 | 5.6 | 3.6 | 6.0 | 5.3 | 5.6 | 6.6 | 7.0 |
L | 6.8 | 7.1 | 6.7 | 7.2 | 6.8 | 8.0 | 7.1 | 5.6 | 7.5 | 7.1 | 6.1 | 6.7 | 7.2 | 7.7 | 7.1 | 7.0 |
M | 1.7 | 1.3 | 1.0 | 0.8 | 0.8 | 1.0 | 1.1 | 0.9 | 0.7 | 1.0 | 0.9 | 1.0 | 1.1 | 1.0 | 1.1 | 1.1 |
N | 2.1 | 2.0 | 2.5 | 2.4 | 2.1 | 2.0 | 1.2 | 1.7 | 1.7 | 2.6 | 2.1 | 2.0 | 2.2 | 2.2 | 2.3 | 2.6 |
P | 8.3 | 9.6 | 9.4 | 10.2 | 9.4 | 11.0 | 11.5 | 15.8 | 11.6 | 12.2 | 17.8 | 12.3 | 9.7 | 10.6 | 8.9 | 8.2 |
Q | 4.7 | 4.3 | 4.4 | 4.4 | 4.7 | 4.2 | 4.5 | 3.9 | 4.9 | 3.9 | 4.2 | 3.9 | 3.6 | 4.0 | 4.9 | 4.2 |
R | 7.5 | 6.5 | 7.5 | 7.2 | 7.5 | 6.8 | 6.2 | 5.1 | 5.9 | 5.8 | 4.7 | 6.5 | 6.9 | 7.5 | 6.7 | 6.8 |
S | 9.4 | 10.6 | 11.5 | 10.1 | 11.8 | 10.3 | 9.0 | 10.3 | 10.4 | 11.3 | 10.8 | 10.3 | 9.6 | 10.1 | 10.5 | 9.1 |
T | 11.5 | 10.8 | 10.6 | 10.2 | 10.1 | 8.3 | 8.0 | 11.2 | 12.0 | 6.8 | 10.9 | 10.2 | 9.5 | 9.7 | 10.0 | 10.4 |
V | 5.2 | 5.8 | 5.4 | 5.2 | 5.5 | 6.7 | 6.0 | 9.7 | 6.2 | 5.1 | 5.4 | 6.1 | 6.0 | 4.5 | 4.9 | 4.8 |
W | 1.0 | 0.6 | 0.5 | 0.8 | 0.5 | 0.9 | 0.8 | 0.5 | 0.6 | 0.7 | 0.5 | 1.0 | 0.6 | 0.5 | 0.5 | 1.3 |
Y | 1.3 | 1.4 | 1.2 | 1.4 | 1.5 | 1.6 | 1.8 | 1.7 | 1.2 | 1.5 | 1.7 | 1.4 | 1.4 | 1.5 | 1.3 | 1.3 |